Hollywood Stars Who've Spoken About Ozempic & Mounjaro — and What They've Said

One of the hottest and most talked-about topics currently swirling around Hollywood is none other than the type 2 diabetes drug Ozempic and its fellow semaglutide supplements, including the obesity medications Wegovy and Mounjaro. The growing interest and discussions surrounding these medications have captured the attention of many. Dr. Ania Jastreboff explains to PEOPLE that these medications are "nutrient-stimulated, hormone-based medications" that specifically target the brain and significantly impact the feeling of satiety. This unique mechanism has led to the drug’s rising popularity in Hollywood as a weight-loss solution, attracting individuals who only need to shed a few pounds, as well as those who have been public about their long-term struggles with obesity. "The Hollywood trend is concerning," warns Dr. Caroline Apovian, co-director of the Center for Weight Management and Wellness at the Brigham and Women's Hospital in Boston, when discussing the target audience for these drugs. "We're not merely talking about stars who want to lose 10 lbs. We're discussing individuals who are facing serious health consequences due to obesity, whose lives may be at risk because of this condition."

"After knee surgery, I started hiking and setting new distance goals each week. I could eventually hike three to five miles every day and a 10-mile straight-up hike on weekends. I felt stronger, more fit and more alive than I’d felt in years.
"I eat my last meal at 4 o’clock, drink a gallon of water a day, and use the WeightWatchers principles of counting points. I had an awareness of [weight-loss] medications, but felt I had to prove I had the willpower to do it. I now no longer feel that way. "I now use [Ozempic - semaglutide] as I feel I need it, as a tool to manage not yo-yoing. The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. I’m absolutely done with the shaming from other people and particularly myself."

— to PEOPLE in December 2023

"In my entire life, I never dreamed that we would be talking about medicines that are providing hope for people like me who have struggled for years with being overweight or with obesity."

— during her open-dialogue conversation An Oprah Special: Shame, Blame and the Weight Loss Revolution on ABC in March 2024

Dr. Phil McGraw

“If someone is using a tool similar to the Ozempic, Mounjaro, semaglutide or tirzepatide to help them get back to health, help them lose weight, which takes the pressure off their heart, this isn’t something they should be criticized about. I say more power to ‘em and don’t feel guilty about it and don’t be shamed from people saying something about it. Tell them to mind their own damn business.”

Margaret Josephs

“After menopause, it’s incredibly hard to lose weight. And then you find yourself shamed for it if you’re heavier than society expects." “It shuts off that constant food noise in my mind, and now my blood work is great. [Before starting Ozempic] I felt like I couldn’t do anything right. It doesn’t matter whether I was eating healthy or exercising; I just couldn't see any results, so I really don’t understand why there’s any shame in it if this medication is genuinely helpful to people.” — to Sherri Shepherd on her podcast Sherri, after openly admitting she had struggled with her weight after going through menopause.

Caroline Stanbury

“After 40, we all know, it’s very, very hard to lose weight. But I met so many 40-year-old women going, ‘How have you done it?’ And I don’t want to lie to you … I used Ozempic, which I think is one of the best tools if you’re able to use it. What did Kate Moss say? ‘Nothing tastes as good as skinny feels.’ There’s something to be said for that.”

— on the Uncut & Uncensored with Caroline Stanbury podcast

“Ozempic, I have to say … is an incredible tool. Why do you need to be miserable if you can get yourself back to where you were? I didn’t want to be different. I didn’t do my face to look like a supermodel. I wanted to be me, but younger.”

— to Us Weekly 

Kelly Clarkson, Oprah, Ashley Benson and more celebs who've talked about semaglutide for weigth loss including Ozempic and Tirzepatide, Wegovy — and where they fall on its usage